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  1. The hemoglobin glycation index (HGI) is the difference between measured and estimated glycation of hemoglobin. However, there is limited evidence to investigate the HGI and the clinical outcomes of acute coron...

    Authors: Jiayu Li, Yanguo Xin, Jingye Li, Li Zhou, Hui Qiu, Aidong Shen, Hui Chen and Hongwei Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:162
    Content type: Research Published on:

  2. Insulin resistance (IR) is an important contributor to the development of hypertension (HTN), and the triglyceride-glucose (TyG) index has been proposed as a simple, reliable marker of IR. This study investiga...

    Authors: Dong-Hwa Lee, Jong Eun Park, So Young Kim, Hyun Jeong Jeon and Jong-Hyock Park
    Citation: Diabetology & Metabolic Syndrome 2022 14:161
    Content type: Research Published on:

  3. Several recent studies have found that Osteocalcin (OCN), a multifunctional protein secreted exclusively by osteoblasts, is beneficial to glucose metabolism and type 2 diabetes mellitus (T2DM). However, the ef...

    Authors: Haiyan Lei, Jun Liu, Wei Wang, Xinyi Yang, Zhouqin Feng, Pu Zang, Bin Lu and Jiaqing Shao
    Citation: Diabetology & Metabolic Syndrome 2022 14:160
    Content type: Research Published on:

  4. Asian Indians (AI) are at high risk for both atherosclerotic diseases (ATH) and diabetes mellitus (DM). We analyze the clustering of these two comorbidities as contributing causes of death in AI versus Non-AI ...

    Authors: Deepak R. Nair, Abhyuday Chauhan and Dhananjay Vaidya
    Citation: Diabetology & Metabolic Syndrome 2022 14:159
    Content type: Research Published on:

  5. We aimed to assess the impact of healthy cardiovascular health (CVH) on diabetic complications, mortality, and life expectancy among people with type 2 diabetes and to explore whether inflammation marker media...

    Authors: Yuan Zhang, Rongrong Yang, Yabing Hou, Yanchun Chen, Shu Li, Yaogang Wang and Hongxi Yang
    Citation: Diabetology & Metabolic Syndrome 2022 14:158
    Content type: Research Published on:

  6. Obstructive sleep apnea is a syndrome characterized by recurrent partial, or complete upper airway collapse during sleep. Although obstructive sleep apnea is common in type 2 diabetes mellitus, the majority of...

    Authors: Alemayehu Wondie, Mitku Mammo Taderegew, Betemariam Girma, Atsede Getawey, Daniel Tsega, Tamene Fetene Terefe, Shimelis Mitiku and Hiwot Berhanu
    Citation: Diabetology & Metabolic Syndrome 2022 14:157
    Content type: Research Published on:

  7. To evaluate the efficacy and safety of finerenone and sodium-glucose cotransporter-2 inhibitors (SGLT2i) on reducing new-onset of atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM) and c...

    Authors: Yaofu Zhang, Junheng Wang, Li Jiang, Tongxin Wang, Zhuang Li, Xiaozhe Fu, Weijun Huang, Yonghua Xiao, Shidong Wang and Jinxi Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:156
    Content type: Review Published on:

  8. Diabetes is associated to a high financial and disease burden, explaining a large proportion of expenditure of the health system in one year. The purpose of this study was to estimate long-term costs and healt...

    Authors: Manuel Antonio Espinoza, Tomas Abbott, Alvaro Passi and Carlos Balmaceda
    Citation: Diabetology & Metabolic Syndrome 2022 14:155
    Content type: Research Published on:

  9. To assess the impact of long-acting insulin analogues, compared to intermediate acting neutral protamine Hagedron (NPH), on maternal, perinatal and neonatal outcomes.

    Authors: Jijiao Wang, Xiaochen Ji, Ting Liu and Nan Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:154
    Content type: Review Published on:

  10. Previous studies have shown inconsistent conclusions regarding the association between incretin-based therapies and the risk of developing gallbladder or biliary diseases. We conducted a meta-analysis to evalu...

    Authors: Meng Yu, Zheng Yang, Chongxin Chen, Yuhuan Lv, Linyu Xiang, Subei Zhao and Rong Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:153
    Content type: Research Published on:

  12. The aim of this systematic review and meta-analysis was to determine the effect of olive leaf extract (OLE) supplementation on cardiovascular-related variables, including lipid, glycemic, inflammatory, liver a...

    Authors: Elham Razmpoosh, Shima Abdollahi, Mahdieh Mousavirad, Cain C. T. Clark and Sepideh Soltani
    Citation: Diabetology & Metabolic Syndrome 2022 14:151
    Content type: Review Published on:

  13. Metabolically healthy obesity (MHO), has been recognized as a transient phenotype with few cardiometabolic diseases; however, little is known regarding the development of hypertension in subjects with an absen...

    Authors: Yue Yuan, Wei Sun and Xiangqing Kong
    Citation: Diabetology & Metabolic Syndrome 2022 14:150
    Content type: Research Published on:

  14. The clustering of metabolic abnormalities may weaken vaccine-induced immunity, but epidemiological data regarding SARS-CoV-2 vaccines are scarce. The present study aimed to examine the cross-sectional associat...

    Authors: Dong Van Hoang, Shohei Yamamoto, Ami Fukunaga, Yosuke Inoue, Tetsuya Mizoue and Norio Ohmagari
    Citation: Diabetology & Metabolic Syndrome 2022 14:149
    Content type: Research Published on:

  15. Diabetes-induced liver injury is a complication of diabetes mellitus of which there are no approved drugs for effective treatment or prevention. This study investigates possible hepatoprotective effect of alph...

    Authors: George J. Dugbartey, Karl K. Alornyo, Ismaila Adams, Stephen Atule, Richard Obeng-Kyeremeh, Daniel Amoah and Samuel Adjei
    Citation: Diabetology & Metabolic Syndrome 2022 14:148
    Content type: Research Published on:

  16. The hypothalamus of the central nervous system is implicated in the development of diabetes due to its glucose-sensing function. Dysregulation of the hypothalamic glucose-sensing neurons leads to abnormal gluc...

    Authors: Edina Pandur, István Szabó, Edina Hormay, Ramóna Pap, Attila Almási, Katalin Sipos, Viktória Farkas and Zoltán Karádi
    Citation: Diabetology & Metabolic Syndrome 2022 14:147
    Content type: Research Published on:

  17. Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be...

    Authors: Christine Haugen, Vegard Lysne, Ingfrid Haldorsen, Erling Tjora, Oddrun Anita Gudbrandsen, Jørn Vegard Sagen, Simon N. Dankel and Gunnar Mellgren
    Citation: Diabetology & Metabolic Syndrome 2022 14:146
    Content type: Research Published on:

  18. Measurement of estimated glucose disposal rate (eGDR) has been demonstrated to be an indicator of insulin resistance (IR) and a risk sign for long-term outcomes in those with ischemic heart disease and type 2 ...

    Authors: Chi Liu, Xiaoli Liu, Xiaoteng Ma, Yujing Cheng, Yan Sun, Dai Zhang, Qi Zhao and Yujie Zhou
    Citation: Diabetology & Metabolic Syndrome 2022 14:145
    Content type: Research Published on:

  19. Maternal complications of pregnancy, including hypertensive disorders of pregnancy, gestational diabetes mellitus, intrauterine growth restriction, preterm labour, and placental abruption, are associated with ...

    Authors: Emily Aldridge, Maleesa Pathirana, Melanie Wittwer, Susan Sierp, Shalem Y. Leemaqz, Claire T. Roberts, Gustaaf A. Dekker and Margaret A. Arstall
    Citation: Diabetology & Metabolic Syndrome 2022 14:144
    Content type: Research Published on:

  20. The nutrition transition in developing countries like Iran causes the increasing rise of obesity and abdominal obesity rates. However, it is not yet well proven that environmental modifications like improving ...

    Authors: Fatemeh Gholami, Mahsa Samadi, Neda Soveid and Khadijeh Mirzaei
    Citation: Diabetology & Metabolic Syndrome 2022 14:143
    Content type: Research Published on:

  21. Increased serum carcinoembryonic antigen (CEA) levels are reported to be associated with various metabolic and inflammatory diseases. This study assessed whether high-normal serum CEA is related to diabetic pe...

    Authors: Chun-hua Wang, Chao Yu, Lei Zhuang, Feng Xu, Li-hua Zhao, Xiao-hua Wang, Li-yan Ning, Xiu-lin Zhang, Dong-mei Zhang, Xue-qin Wang and Jian-bin Su
    Citation: Diabetology & Metabolic Syndrome 2022 14:142
    Content type: Research Published on:

  22. This study aimed to evaluate whether soluble vascular cytoadhesive molecule-1 (sVCAM-1), intracellular cytoadhesive molecule-1 (sICAM-1), and endothelial function as assessed by EndoPat outweighed traditional ...

    Authors: Alessandra Saldanha de Mattos Matheus, Maria de Fátima Bevilacqua da Matta, Eliete Leão Silva Clemente, Maria de Lourdes Guimarães Rodrigues, Débora Cristina Torres Valença, Karla Rezende Guerra Drummond and Marília Brito Gomes
    Citation: Diabetology & Metabolic Syndrome 2022 14:141
    Content type: Research Published on:

  23. An interprofessional medication adherence intervention led by pharmacists, combining motivational interviews and feedback with electronic monitor (EM) drug assessment, was offered to all consecutive patients w...

    Authors: Carole Bandiera, Liliane Lam, Isabella Locatelli, Jennifer Dotta-Celio, Dina Duarte, Gregoire Wuerzner, Menno Pruijm, Anne Zanchi and Marie P. Schneider
    Citation: Diabetology & Metabolic Syndrome 2022 14:140
    Content type: Research Published on:

  24. The purpose of this study was to investigate the psychometric properties of the Persian version of Diabetes Health Literacy Scale in type 2 diabetic patients.

    Authors: Mahdi Moshki, Ali Alami, Zohreh Zadehahmad, Mousa Ghelichi-Ghojogh, Mitra Dogonchi and Alireza Jafari
    Citation: Diabetology & Metabolic Syndrome 2022 14:139
    Content type: Research Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2022 14:174

  25. Chinese diabetes society has published the new diagnostic criteria for diabetes in China (2020 edition). We aimed to investigate the predictive value of new diabetes-diagnosed criteria for cardiovascular disea...

    Authors: Zixiang Ye, Yanxiang Gao, Enmin Xie, Yike Li, Ziyu Guo, Peizhao Li, Jingyi Ren and Jingang Zheng
    Citation: Diabetology & Metabolic Syndrome 2022 14:138
    Content type: Research Published on:

  26. Several studies have investigated the association of insulin resistance (IR) surrogates and the risk of hypertension. However, it is unclear whether there exist differences between different IR surrogates and ...

    Authors: Wenke Cheng, Fanliang Kong and Siwei Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:137
    Content type: Research Published on:

  27. Previous studies suggest intestinal dysbiosis is associated with metabolic diseases. However, the causal relationship between them is not fully elucidated. Gut microbiota evaluation of patients with congenital...

    Authors: Renan Magalhães Montenegro Junior, Clarisse Mourão Melo Ponte, Maria Helane Costa Gurgel Castelo, Alessandro Conrado de Oliveira Silveira, Virgínia Oliveira Fernandes, Catarina Brasil D’Alva, Luiz Felipe Valter Oliveira, Angélica Domingues Hristov, Silviane Praciano Bandeira, Grayce Ellen da Cruz Paiva and José Eduardo Levi
    Citation: Diabetology & Metabolic Syndrome 2022 14:136
    Content type: Research Published on:

  28. Salvianolic acid A (SalA) is the main water-soluble component isolated from Salvia miltiorrhiza. This study explored the influences of SalA on intestinal microbiota composition and lipid metabolism in Zucker diab...

    Authors: Xufeng Wang, Xiangjun Sun, Abulikemu Abulizi, Jinyao Xu, Yun He, Qian Chen and Ruicheng Yan
    Citation: Diabetology & Metabolic Syndrome 2022 14:135
    Content type: Research Published on:

  29. There is an increased burden of diabetes globally including in sub-Saharan Africa. The literature shows that glycaemic control among type 2 diabetes patients is poor in most countries in sub-Saharan Africa. Un...

    Authors: Jean-Pierre Fina Lubaki, Olufemi Babatunde Omole and Joel Msafiri Francis
    Citation: Diabetology & Metabolic Syndrome 2022 14:134
    Content type: Research Published on:

  30. Diabetic foot ulcer (DFU) is a common diabetes mellitus (DM) complication. Individuals with DM and a DFU achieved significantly lower scores in cognitive tests than those without a DFU. We investigated whether...

    Authors: Yael Sela, Keren Grinberg, Tali Cukierman-Yaffe and Rachel Natovich
    Citation: Diabetology & Metabolic Syndrome 2022 14:133
    Content type: Research Published on:

  31. We aimed to investigate the joint effect of visit-to-visit variability (VVV) in low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides and glycosylated hemoglo...

    Authors: Panpan He, Xiaoqin Gan, Qimeng Wu, Ziliang Ye, Sisi Yang, Yanjun Zhang, Huan Li, Chun Zhou, Yuanyuan Zhang, Mengyi Liu and Xianhui Qin
    Citation: Diabetology & Metabolic Syndrome 2022 14:132
    Content type: Research Published on:

  33. Ambulatory blood pressure monitoring (ABPM) in patients with diabetes mellitus (DM) and hypertension (HTN) show the dipping patterns, identify masked uncontrolled hypertension (MUCH), and demonstrate the effec...

    Authors: Pop Călin, Manea Viorel, Pruna Luchiana, Cosma Mihaela and Pop Lavinia
    Citation: Diabetology & Metabolic Syndrome 2022 14:130
    Content type: Research Published on:

  34. A main factor contributing to insufficient glycemic control, during basal/bolus insulin therapy, is poor self-management bolus. Insulin bolus administration frequency is strongly associated with glycated hemog...

    Authors: Vanessa Araujo Montanari, Mônica Andrade Lima Gabbay and Sérgio Atala Dib
    Citation: Diabetology & Metabolic Syndrome 2022 14:129
    Content type: Research Published on:

  35. Type 1 diabetes (T1D) and celiac disease (CD) coexist very often. Identification of the human leukocyte antigen (HLA) DQ2/DQ8 can confirm the genetic predisposition to CD. Negative result of this test allows t...

    Authors: Agnieszka Zubkiewicz-Kucharska, Tatiana Jamer, Joanna Chrzanowska, Katarzyna Akutko, Tomasz Pytrus, Andrzej Stawarski and Anna Noczyńska
    Citation: Diabetology & Metabolic Syndrome 2022 14:128
    Content type: Research Published on:

  36. Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue. PAI-1 inhibits tissue plasminogen activa...

    Authors: Gaber El-Saber Batiha, Hayder M. Al-kuraishy, Thabat J. Al-Maiahy, Ali K. Al-Buhadily, Hebatallah M. Saad, Ali I. Al-Gareeb and Jesus Simal-Gandara
    Citation: Diabetology & Metabolic Syndrome 2022 14:127
    Content type: Review Published on:

  37. Hyperglycemic non-diabetic stroke patients have a worse prognosis than both normoglycemic and diabetic patients. Aim of this study was to assess whether hyperglycemia is an aggravating factor or just an epiphe...

    Authors: Antonio Muscari, Roberta Falcone, Guerino Recinella, Luca Faccioli, Paola Forti, Marco Pastore Trossello, Giovanni M. Puddu, Luca Spinardi and Marco Zoli
    Citation: Diabetology & Metabolic Syndrome 2022 14:126
    Content type: Research Published on:

  38. Interleukin-6 (IL-6) is an inflammation-related cytokine associated with an elevated risk of cardiovascular events. In a previous study, we demonstrated that increased IL-6 was predictive of sub-clinical ather...

    Authors: Márcio Mossmann, Marco Vugman Wainstein, Stéfani Mariani, Guilherme Pinheiro Machado, Gustavo Neves de Araújo, Michael Andrades, Sandro Cadaval Gonçalves and Marcello Casaccia Bertoluci
    Citation: Diabetology & Metabolic Syndrome 2022 14:125
    Content type: Research Published on:

  39. As one of the severe complications of diabetes mellitus, diabetic retinopathy (DR) is the leading cause of blindness in the working age worldwide. Although panretinal photocoagulation (PRP) was standard treatm...

    Authors: Jinglan Li, Xuanlong Li, Mingxing Lei, Wanyue Li, Wenqian Chen, Tianju Ma, Yi Gao, Zi Ye and Zhaohui Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:124
    Content type: Research Published on:

  40. Gaussian graphical models (GGM) are an innovative method for deriving dietary networks which reflect dietary intake patterns and demonstrate how food groups are consuming in relation to each other, independent...

    Authors: Reihaneh Jahanmiri, Kurosh Djafarian, Nasim Janbozorgi, Fatemeh Dehghani-Firouzabadi and Sakineh Shab-Bidar
    Citation: Diabetology & Metabolic Syndrome 2022 14:123
    Content type: Research Published on:

  41. Diabetes-induced chronic hyperglycemia results in the formation and aggregation of advanced glycation end-products (AGEs), which are products of non-enzymatic glycosylation of lipids or proteins. The developme...

    Authors: Mohaddeseh Rezaei, Soghra Rabizadeh, Maryam Mirahmad, Minoo Sadat Hajmiri, Manouchehr Nakhjavani, Mahboobeh Hemmatabadi and Nooshin Shirzad
    Citation: Diabetology & Metabolic Syndrome 2022 14:122
    Content type: Research Published on:

  42. Glucose cotransporter (SGLT) 2 suppression provides potent renal protective effect during diabetic kidney disease (DKD). This work aimed to explore how empagliflozin (EMPA, the selective and strong inhibitor o...

    Authors: Hong Sun, Juan Chen, Yulin Hua, Yuyang Zhang and Zheng Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:121
    Content type: Research Published on:

  43. Type 2 Diabetes mellitus is one of the most common chronic diseases in the world and has many complications. Due to the importance of using alternative therapies in managing symptoms of this disease, the prese...

    Authors: Shima Nematollahi, Gholam Reza Pishdad, Mehrnoosh Zakerkish, Foroogh Namjoyan, Kambiz Ahmadi Angali and Fatemeh Borazjani
    Citation: Diabetology & Metabolic Syndrome 2022 14:120
    Content type: Research Published on:

  44. Metabolic syndrome (MetS) is a cluster of conditions associated with glucose intolerance, hypertension, abdominal obesity, dyslipidemia, and insulin resistance that increase the risk of cardiovascular diseases...

    Authors: Sanghoo Lee, Seol-A Kim, Jeonghoon Hong, Yejin Kim, Gayeon Hong, SaeYun Baik, Kyeonghwan Choi, Mi-Kyeong Lee and Kyoung-Ryul Lee
    Citation: Diabetology & Metabolic Syndrome 2022 14:119
    Content type: Research Published on:

  46. Obesity and related metabolic disorders are associated with genetic and epigenetic alterations. In this study, we have examined the association between polymorphisms and hypermethylation of the CD36 gene promoter...

    Authors: Maïmouna Touré, Aziz Hichami, Amira Sayed, Muhtadi Suliman, Abdoulaye Samb and Naim Akhtar Khan
    Citation: Diabetology & Metabolic Syndrome 2022 14:117
    Content type: Research Published on:

  47. Peripheral and central hemodynamic indices are modifiable by lifestyle and medical intervention. We aimed to determine the long-term effect of intensive multifactorial treatment on peripheral and central hemod...

    Authors: Lasse Bjerg, Esben Laugesen, Signe Toft Andersen, Jonas Frey Rosborg, Morten Charles, Dorte Vistisen and Daniel R. Witte
    Citation: Diabetology & Metabolic Syndrome 2022 14:116
    Content type: Research Published on:

  48. Metabolic dysfunction and associated systemic inflammation are risk factors for chronic obstructive pulmonary disease (COPD) and COPD is highly prevalent in men. We investigated the impact of metabolic-associa...

    Authors: Tsubasa Tsutsumi, Dan Nakano, Machiko Kawaguchi, Ryuki Hashida, Shinobu Yoshinaga, Hirokazu Takahashi, Keizo Anzai and Takumi Kawaguchi
    Citation: Diabetology & Metabolic Syndrome 2022 14:115
    Content type: Research Published on:

  50. The β-cell function and insulin resistance required by existing methods of classifying type 2 diabetes are not routinely adopted in most medical institutions of developing countries and regions. This study aim...

    Authors: Jing Xie, Xin Zhang, Hua Shao, Shenqi Jing, Tao Shan, Yaxiang Shi, Yong Li, Yun Liu and Naifeng Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:113
    Content type: Research Published on:

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