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Table 2 Heterogeneity and Pleiotropy tests of MR.

From: Mendelian randomisation highlights type 1 diabetes as a causal determinant of idiopathic pulmonary fibrosis

Test

Method

Effect size

P

Heterogeneity

Q MR Egger

39.946

0.259

 

Q IVW

40.375

0.282

Pleiotropy

MR-Egger regression

0.0103

0.543

  1. Q: Cochran’s Q test; MR: Mendelian randomization; IVW: inverse variance weighted