Table 1 Patient demographics and baseline characteristics

Age (years)

48 ± 18

51 ± 18

48 ± 18

47 ± 18

49 ± 19

< 0.001

BMI

29 ± 7

29 ± 7

29 ± 7

29 ± 7

30 ± 7

< 0.001

Gender

< 0.001

Male

6,433 (48%)

1,340 (40%)

1,444 (43%)

1,688 (51%)

1,961 (59%)

Female

6,882 (52%)

1,978 (60%)

1,890 (57%)

1,641 (49%)

1,373 (41%)

Race

< 0.001

Mexican American

2,013 (15%)

409 (12%)

476 (14%)

589 (18%)

539 (16%)

Non-Hispanic Black

1,434 (11%)

339 (10%)

384 (12%)

352 (11%)

359 (11%)

Non-Hispanic White

5,251 (39%)

1,035 (31%)

1,320 (40%)

1,393 (42%)

1,503 (45%)

Other Hispanic

2,753 (21%)

1,087 (33%)

655 (20%)

490 (15%)

521 (16%)

Other Race - Including Multi-Racial

1,864 (14%)

448 (14%)

499 (15%)

505 (15%)

412 (12%)

Smoke

< 0.001

Every day

2,034 (15%)

576 (17%)

518 (16%)

482 (14%)

458 (14%)

Some days

502 (4%)

114 (3%)

122 (4%)

123 (4%)

143 (4%)

Not at all

3,050 (23%)

696 (21%)

697 (21%)

743 (22%)

914 (27%)

Other

7,729 (58%)

1,932 (58%)

1,997 (60%)

1,981 (60%)

1,819 (55%)

Monocyte (1000 cells/uL)

0.53 ± 0.21

0.54 ± 0.19

0.53 ± 0.18

0.53 ± 0.25

0.54 ± 0.19

0.138

NEU (1000 cell/uL)

3.98 ± 1.77

3.90 ± 2.16

3.91 ± 1.64

3.97 ± 1.56

4.14 ± 1.66

< 0.001

Hemoglobin (g/dL)

14.06 ± 1.54

13.58 ± 1.52

13.97 ± 1.45

14.26 ± 1.44

14.42 ± 1.59

< 0.001

PLT (1000 cells/uL)

236 ± 62

240 ± 66

239 ± 62

235 ± 60

229 ± 62

< 0.001

RBC (million cells/uL)

4.69 ± 0.51

4.62 ± 0.52

4.68 ± 0.50

4.73 ± 0.49

4.74 ± 0.53

< 0.001

WBC (1000 cells/uL)

6.82 ± 2.48

6.77 ± 2.65

6.80 ± 2.89

6.81 ± 2.19

6.92 ± 2.09

0.064

BUN (mmol/L)

4.89 ± 2.13

4.96 ± 2.33

4.75 ± 1.97

4.80 ± 1.87

5.04 ± 2.29

< 0.001

Creatinine (umol/L)

79 ± 42

81 ± 50

76 ± 31

77 ± 39

81 ± 46

< 0.001

Albumin (g/dL)

4.21 ± 0.35

4.14 ± 0.36

4.20 ± 0.33

4.24 ± 0.33

4.24 ± 0.37

< 0.001

AST (U/L)

25 ± 19

25 ± 20

25 ± 24

25 ± 14

26 ± 17

0.019

ALT (U/L)

25 ± 18

23 ± 16

24 ± 17

25 ± 19

27 ± 20

< 0.001

Potassium (mmol/L)

4.03 ± 0.35

4.03 ± 0.36

4.03 ± 0.34

4.02 ± 0.34

4.02 ± 0.36

0.779

Sodium (mmol/L)

139.45 ± 2.32

139.44 ± 2.32

139.52 ± 2.25

139.49 ± 2.24

139.34 ± 2.46

0.007

Congestive heart failure

< 0.001

Yes

438 (3%)

130 (4%)

94 (3%)

84 (3%)

130 (4%)

No

12,877 (97%)

3,188 (96%)

3,240 (97%)

3,245 (97%)

3,204 (96%)

Coronary heart disease

0.001

Yes

533 (4%)

153 (5%)

103 (3%)

120 (4%)

157 (5%)

No

12,782 (96%)

3,165 (95%)

3,231 (97%)

3,209 (96%)

3,177 (95%)

Stroke

0.005

Yes

497 (4%)

140 (4%)

118 (4%)

95 (3%)

144 (4%)

No

12,818 (96%)

3,178 (96%)

3,216 (96%)

3,234 (97%)

3,190 (96%)

Emphysema

0.296

Yes

254 (2%)

74 (2%)

58 (2%)

55 (2%)

67 (2%)

No

13,061 (98%)

3,244 (98%)

3,276 (98%)

3,274 (98%)

3,267 (98%)

Cancer or malignancy

0.149

Yes

1,195 (9%)

315 (9%)

290 (9%)

272 (8%)

318 (10%)

No

12,120 (91%)

3,003 (91%)

3,044 (91%)

3,057 (92%)

3,016 (90%)