Parameter in control | Beginning 2018 n(%) | End of 2018 n(%) | Beginning 2019 n(%) | End of 2019 n(%) | Beginning 2020 n(%) | End of 2020 n(%) | Beginning 2021 n(%) | End of 2021 n(%) | Beginning 2022 n(%) | End of 2022 n(%) | p-value1 |
---|---|---|---|---|---|---|---|---|---|---|---|
Fasting Serum Glucose | 110 (13.8) n = 796 | 126 (16.3) n = 775 | 488 (56.2) n = 869 | 491 (55.2) n = 889 | 421 (54.8) n = 768 | 476 (56.5) n = 843 | 455 (54.6) n = 833 | 285 (59.5) n = 479 | 378 (50.6) n = 747 | 407 (56.1) n = 726 | < 0.001 |
Glycated Hemoglobin | 493 (55.5) n = 888 | 308 (53.2) n = 579 | 171 (53.8) n = 318 | 586 (61.3) n = 956 | 261 (64.3) n = 406 | 96 (73.8) n = 130 | 461 (61.7) n = 747 | 410 (70.8) n = 579 | 373 (61.9) n = 603 | 490 (70.7) n = 693 | < 0.001 |
HDL-C | 415 (62.9) n = 660 | 372 (60.1) n = 619 | 379 (61.1) n = 620 | 401 (59.1) n = 679 | 325 (57.2) n = 568 | 412 (58) n = 710 | 361 (55.6) n = 649 | 157 (50.2) n = 313 | 689 (87.0) n = 792 | 277 (48.6) n = 570 | < 0.001 |
LDL-C | 406 (62.1) n = 654 | 403 (66.0) n = 611 | 384 (62.2) n = 617 | 403 (59.4) n = 679 | 298 (52.7) n = 566 | 387 (55.0) n = 704 | 385 (59.0) n = 653 | 173 (53.2) n = 325 | 476 (69.7) n = 683 | 326 (57.0) n = 572 | < 0.001 |
Triglycerides | 356 (53.9) n = 660 | 354 (56.9) n = 622 | 338 (53.8) n = 628 | 394 (57.1) n = 690 | 305 (53.1) n = 574 | 389 (54.6) n = 712 | 333 (51.2) n = 650 | 150 (47.5) n = 316 | 322 (53.4) n = 603 | 299 (52.5) n = 570 | 0.161 |
Negative Albuminuria | 64 (80.5) n = 74 | 263 (83.0) n = 317 | 247 (81.0) n = 305 | 316 (82.1) n = 385 | 208 (86.3) n = 241 | 230 (75.4) n = 305 | 266 (82.4) n = 323 | 47 (81.0) n = 58 | 250 (87.4) n = 683 | 219 (89.0) n = 246 | 0.002 |
FIB-4 0–1 Classification | 199 (65) | n = 307 | 67 (46) | n = 145 | 169 (64) | n = 264 | 234 (59) | n = 396 | 79 (72) | n = 110 | < 0.001 |
FIB-4 2 Classification | 93 (30) | n = 307 | 62 (43) | n = 145 | 82 (31) | n = 264 | 129 (33) | n = 396 | 23 (21) | n = 110 | < 0.001 |
FIB-4 3–4 Classification | 15 (4.9) | n = 307 | 16 (11) | n = 145 | 13 (4.9) | n = 264 | 33 (8.3) | n = 396 | 8 (7.3) | n = 110 | < 0.001 |
Systolic blood pressure | 563 (82.7) n = 681 | 559 (83.4) n = 670 | 580 (84.8) n = 684 | 394 (86.6) n = 455 | 212 (89.8) n = 236 | 127 (86.4) n = 147 | 424 (81.1) n = 523 | 505 (82.8) n = 610 | 607 (78.1) n = 777 | 640 (80.1) n = 799 | < 0.001 |
Diastolic blood pressure | 612 (89.6) n = 683 | 623 (93) n = 670 | 625 (91.2) n = 685 | 417 (91.4) n = 456 | 211 (89.4) n = 236 | 135 (91.2) n = 148 | 446 (87.1) n = 512 | 684 (88.1) n = 776 | 684 (88.1) n = 776 | 729 (91.4) n = 798 | 0.01 |
Body mass index | 23 (6.0) n = 383 | 30 (7.6) n = 395 | 34 (7.0) n = 486 | 62 (7.6) n = 818 | 53 (7.2) n = 736 | 15 (10.1) n = 148 | 17 (8.7) n = 196 | 43 (14) n = 297 | 57 (12) n = 489 | 80 (12) n = 678 | < 0.001 |