Laboratory Parameter Mean (SD) | Beginning 2018 | End of 2018 | Beginning 2019 | End of 2019 | Beginning 2020 | End of 2020 | Beginning 2021 | End of 2021 | Beginning 2022 | End of 2022 | p-value |
---|---|---|---|---|---|---|---|---|---|---|---|
Fasting Serum Glucose (mg/dL) | 163.8 (1.3)a n = 796 | 159.8 (1.3)a n = 775 | 124.9 (1.4)b n = 869 | 126.5 (1.4)b n = 890 | 127.9 (1.4)c n = 768 | 126.0 (1.4)c n = 843 | 128.5 (1.4)c n = 833 | 124.8 (1.3)c n = 479 | 132.3 (1.4)b n = 747 | 130.2 (1.4)b n = 726 | < 0.001 |
Glycated Hemoglobin (%) | 7.3 (1.2) n = 888 | 7.4 (1.2) n = 582 | 7.2 (1.2) n = 320 | 7.2 (1.2) n = 956 | 7.3 (1.2) n = 406 | 7.1 (1.2) n = 130 | 7.4 (1.2) n = 747 | 7.1 (1.2) n = 578 | 7.3 (1.2) n = 603 | 7.1 (1.2) n = 693 | 0.941 |
Total Cholesterol (mg/dL) | 166.9 (1.2) n = 795 | 163.6 (1.2) n = 771 | 165.5 (1.3) n = 772 | 165.1 (1.3) n = 837 | 164.7 (1.3) n = 718 | 160.7 (1.3) n = 830 | 162.2 (1.2) n = 725 | 161.5 (1.2) n = 502 | 159.0 (1.3) n = 476 | 162.2 (1.3) n = 558 | 0.660 |
HDL-C (mg/dL) | 41.4 (1.3) n = 660 | 41.9 (1.3) n = 619 | 42.0 (1.3) n = 620 | 42.6 (1.3) n = 679 | 42.8 (1.2) n = 568 | 43.0 (1.3) n = 710 | 43.4 (1.3) n = 649 | 44.5 (1.3) n = 313 | 44.5 (1.3) n = 621 | 45.2 (1.3) n = 570 | 0.102 |
LDL-C (mg/dL) | 88.6 (1.4) n = 654 | 86.3 (1.4) n = 611 | 86.1 (1.5) n = 617 | 87.8 (1.5) n = 679 | 95.3 (1.4) n = 566 | 93.9 (1.4) n = 704 | 91.4 (1.4) n = 645 | 93.1 (1.5) n = 318 | 95.5 (1.4) n = 308 | 90.4 (1.4) n = 567 | 0.368 |
Triglycerides (mg/dL) | 151.9 (1.6) n = 660 | 142.2 (1.6) n = 622 | 151.8 (1.6) n = 628 | 144.4 (1.6) n = 690 | 149.1 (1.6) n = 574 | 147.6 (1.7) n = 712 | 151.6 (1.7) n = 650 | 159.7 (1.7) n = 316 | 150.6 (1.7) n = 603 | 149.9 (1.6) n = 570 | 0.834 |
Systolic blood pressure (mmHg) | 123.2 (1.1) n = 681 | 122.8 (1.1) n = 670 | 122.8 (1.1) n = 684 | 122 (1.1) n = 455 | 119.9 (1.1) n = 237 | 120.7 (1.1) n = 147 | 122.5 (1.1) n = 523 | 122.3 (1.1) n = 610 | 124.0 (1.1) n = 777 | 122.8 (1.1) n = 799 | 0.799 |
Diastolic blood pressure (mmHg) | 74.3 (1.1) n = 683 | 73.8 (1.1) n = 670 | 74.0 (1.1) n = 685 | 72.2 (1.1) n = 456 | 71.6 (1.1) n = 236 | 70.8 (1.1) n = 148 | 75.1 (1.1) n = 512 | 74.9 (1.1) n = 609 | 74.7 (1.1) n = 776 | 73.3 (1.1) n = 799 | 0.133 |
Body mass index (kg/m2) | 31.4 (1.2) n = 383 | 31.1 (1.2) n = 395 | 31.2 (1.2) n = 486 | 31.0 (1.2) n = 818 | 31.2 (1.2) n = 736 | 31.1 (1.2) n = 148 | 31.1 (1.2) n = 196 | 30.2 (1.2) n = 297 | 30.4 (1.2) n = 489 | 30.3 (1.2) n = 678 | 0.636* |