Fig. 6From: High glucose-induced injury in human umbilical vein endothelial cells is alleviated by vitamin D supplementation through downregulation of TIPE1?Serum vitamin D level was negatively associated with TIPE1 level in type 2 diabetes patients. (A) Relative mRNA level of TIPE1 was detected in type 2 diabetes mellitus patients with or without microvascular complications by RT-qPCR. (B) Pearson correlation analysis of the mRNA expression of TIPE1 and serum vitamin D level in type 2 diabetes mellitus patients with or without microvascular complications. (C) The 1000 bp upstream promoter sequences of TIPE1 from the Ensemble website. (D) Potential binding sites of VDR on 1000 bp upstream promoter sequences of TIPE1 from the JASPAR website. (E) Possible function mechanisms of vitamin D on TIPE1 expressions. *P<0.05Back to article page