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Table 2 Pancreatic parenchymal volumes were estimated in all ten patients by two single board-certified radiologists. Pancreatic volumes were calculated from CT or MRI scans at four time points, including before immunotherapy initiation (baseline), at the last image available before ICI-DM onset (pre-DM), at ICI-DM onset (DM), and at the last image available after diabetes onset (last follow-up)

From: Distinct changes to pancreatic volume rather than pancreatic autoantibody positivity: insights into immune checkpoint inhibitors induced diabetes mellitus

Time of Pancreas Volume Measurement

Median (Range), cm3

Wilcoxon Rank Sum Test p Value

Median Percent Change (Range)

Baseline

75.80 (44.97, 112.83)

Reference

Reference

Pre-DM

60.01 (44.95, 91.99)

0.068

-14.99% (-33.84%, -0.04%)

DM

63.86 (33.92, 84.34)

0.038 *

-19.92% (-37.17%, + 11.42%)

Last follow-up

55.60 (21.38, 74.84)

0.012 *

-37.14% (-60.39%, -7.13%)