Presence of metabolic syndrome | MET score | N | Events | Person-years | Incidence rate per 1000 | Univariate model | Multivariate model 1 | Multivariate model 2 | Multivariate model 3 |
---|---|---|---|---|---|---|---|---|---|
All-cause mortality | |||||||||
MS (−) | Totally sedentary | 1709997 | 67818 | 14057952.64 | 4.824 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
1–499 | 2473546 | 53916 | 20456279.16 | 2.636 | 0.55 (0.54, 0.55) | 0.85 (0.84, 0.86) | 0.87 (0.86, 0.88) | 0.87 (0.86, 0.88) | |
500–999 | 2068214 | 51171 | 17110004.09 | 2.990 | 0.62 (0.61, 0.63) | 0.81 (0.80, 0.82) | 0.84 (0.83, 0.85) | 0.84 (0.83, 0.85) | |
1000–1499 | 759903 | 18762 | 6297310.76 | 2.979 | 0.62 (0.61, 0.63) | 0.74 (0.73, 0.75) | 0.79 (0.78, 0.80) | 0.79 (0.78, 0.80) | |
≥ 1500 | 362759 | 13157 | 2996779.46 | 4.390 | 0.91 (0.89, 0.93) | 0.76 (0.75, 0.78) | 0.82 (0.81, 0.84) | 0.83 (0.81, 0.84) | |
P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||||
MS ( +) | Totally sedentary | 591380 | 45942 | 4809944.99 | 9.551 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
1–499 | 691591 | 33941 | 5672370.44 | 5.984 | 0.63 (0.62, 0.64) | 0.85 (0.83, 0.86) | 0.86 (0.85, 0.87) | 0.86 (0.85, 0.87) | |
500–999 | 607456 | 31689 | 4981576.91 | 6.361 | 0.67 (0.66, 0.68) | 0.80 (0.79, 0.81) | 0.82 (0.81, 0.83) | 0.82 (0.81, 0.83) | |
1000–1499 | 237353 | 11466 | 1951561.18 | 5.875 | 0.62 (0.60, 0.63) | 0.72 (0.71, 0.74) | 0.75 (0.74, 0.77) | 0.76 (0.74, 0.77) | |
≥ 1500 | 125910 | 8108 | 1030530.11 | 7.868 | 0.82 (0.81, 0.84) | 0.74 (0.72, 0.76) | 0.78 (0.76, 0.80) | 0.78 (0.77, 0.80) | |
P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||||
P for interaction | < 0.001 | 0.248 | < 0.001 | < 0.001 | |||||
Incident cardiovascular diseases | |||||||||
MS (−) | Totally sedentary | 1709997 | 33603 | 13950759.84 | 2.409 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
1–499 | 2473546 | 29232 | 20362317.67 | 1.436 | 0.60 (0.59, 0.61) | 0.84 (0.83, 0.86) | 0.87 (0.85, 0.88) | 0.89 (0.87, 0.90) | |
500–999 | 2068214 | 27174 | 17022721.37 | 1.596 | 0.66 (0.65, 0.67) | 0.82 (0.80, 0.83) | 0.84 (0.83, 0.86) | 0.85 (0.81, 0.87) | |
1000–1499 | 759903 | 10386 | 6263598.83 | 1.658 | 0.69 (0.67, 0.70) | 0.78 (0.76, 0.79) | 0.82 (0.80, 0.83) | 0.83 (0.81, 0.84) | |
≥ 1500 | 362759 | 6790 | 2974979.44 | 2.282 | 0.95 (0.92, 0.97) | 0.81 (0.79, 0.83) | 0.85 (0.83, 0.87) | 0.85 (0.83, 0.87) | |
P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||||
MS ( +) | Totally sedentary | 591380 | 29762 | 4712057.42 | 6.316 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
1–499 | 691591 | 24811 | 5590106.32 | 4.438 | 0.70 (0.69, 0.71) | 0.90 (0.88, 0.92) | 0.91 (0.90, 0.93) | 0.89 (0.88, 0.91) | |
500–999 | 607456 | 22478 | 4907373.12 | 4.580 | 0.73 (0.71, 0.74) | 0.84 (0.83, 0.86) | 0.87 (0.85, 0.88) | 0.86 (0.84, 0.87) | |
1000–1499 | 237353 | 8280 | 1923443.14 | 4.305 | 0.68 (0.66, 0.70) | 0.77 (0.75, 0.79) | 0.81 (0.79, 0.83) | 0.80 (0.78, 0.82) | |
≥ 1500 | 125910 | 5384 | 1012460.19 | 5.318 | 0.84 (0.82, 0.87) | 0.77 (0.75, 0.79) | 0.81 (0.79, 0.84) | 0.82 (0.80, 0.84) | |
P for trend | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||||
P for interaction | < 0.001 | < 0.001 | < 0.001 | < 0.001 |