| Death | Adjusted model 1 | Adjusted model 2 | Adjusted model 3 | Adjusted model 4 | Adjusted model 5 | Adjusted model 6 |
---|---|---|---|---|---|---|---|
 | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
 | 1959 | All-cause mortality | |||||
Q1 | 341 | Reference | Reference | Reference | Reference | Reference | Reference |
Q2 | 403 | 1.06 (0.89–1.26)c | 1.06 (0.88–1.29)c | 0.99 (0.79–1.23)c | 0.97 (0.78–1.19)c | 0.97 (0.79–1.18)c | 0.95 (0.77–1.16)c |
Q3 | 489 | 1.22 (1.02–1.46) a | 1.13 (1.05–1.21)a | 1.18 (0.93–1.49)c | 1.10 (0.88–1.38)c | 1.08 (0.87–1.34)c | 1.01 (0.82–1.25)c |
Q4 | 726 | 1.81 (1.52–2.14)b | 2.09 (1.73–2.53)b | 1.66 (1.35–2.04)b | 1.47 (1.20–1.81)b | 1.43 (1.18–1.75)b | 1.30 (1.07–1.58)a |
P for trend |  |  < 0.001 |  < 0.001 |  < 0.001 |  < 0.001 |  < 0.001 |  < 0.001 |
Per SD increase |  | 1.23 (1.16–1.31)b | 1.27 (1.22–1.34)b | 1.20 (1.15–1.26)b | 1.18 (1.13–1.24)b | 1.18 (1.11–1.25)b | 1.16 (1.09–1.23)b |
 | 553 | Cardiovascular disease mortality | |||||
Q1 | 90 | Reference | Reference | Reference | Reference | Reference | Reference |
Q2 | 93 | 0.91 (0.66–1.27)c | 0.89 (0.62–1.29)c | 0.88 (0.58–1.34)c | 0.83 (0.55–1.27)c | 0.83 (0.55–1.26)c | 0.87 (0.57–1.33)c |
Q3 | 131 | 1.17 (0.86–1.58)c | 1.14 (0.81–1.59)c | 1.09 (0.73–1.62)c | 0.98 (0.66–1.48)c | 0.96 (0.64–1.42)c | 0.88 (0.59–1.30)c |
Q4 | 239 | 2.16 (1.55–3.01)b | 2.02 (1.41–2.88)b | 1.99 (1.32–2.99)a | 1.70 (1.12–2.59)a | 1.62 (1.08–2.42)a | 1.57 (1.05–2.37)a |
P for trend |  |  < 0.001 |  < 0.001 |  < 0.001 |  < 0.001 | 0.002 | 0.004 |
Per SD increase |  | 1.28 (1.18–1.39)b | 1.33 (1.24–1.41)b | 1.25 (1.16–1.34)b | 1.24 (1.14–1.34)b | 1.22 (1.11–1.35)b | 1.22 (1.10–1.36)b |