Table 1 Survey-weighted baseline characteristics of the obese population in NHANES from 1999 to 2014 according to SIRI quartiles (N = 13,026, representing 63,479,085 individuals with obesity)

Participants, n

3255

3254

3252

3265

Monocytes (× 10³ cells/ml)

0.43 (0.41, 0.44)

0.51 (0.51, 0.52)

0.59 (0.58, 0.60)

0.72 (0.71, 0.73)

Lymphocytes (× 10³ cells/ml)

2.45 (2.38, 2.53)

2.30 (2.27, 2.33)

2.25 (2.21, 2.28)

2.08 (2.05, 2.11)

Neutrophils (× 10³ cells/ml)

3.11 (3.07, 3.16)

4.01 (3.96, 4.05)

4.76 (4.71, 4.81)

6.14 (6.07, 6.22)

Age (years)

44.9 (44.3, 45.6)

45.3 (44.7, 45.9)

46.6 (45.9, 47.3)

47.7 (47.0, 48.5)

Poverty income ratio

2.7 (2.6, 2.8)

2.9 (2.8, 3.0)

2.9 (2.8, 3.0)

2.8 (2.7, 2.9)

Body mass index (Kg/m²)

35.3 (35.0, 35.6)

35.4 (35.1, 35.6)

35.8 (35.5, 36.0)

36.4 (36.1, 36.8)

HDL (mmol/L)

1.3 (1.2, 1.3)

1.2 (1.2, 1.2)

1.2 (1.2, 1.2)

1.2 (1.2,1.2)

TC (mmol/L)

5.2 (5.2, 5.3)

5.2 (5.1, 5.2)

5.1 (5.1, 5.2)

5.1 (5.0, 5.1)

eGFR

98.7 (97.6,99.7)

96.3 (95.3,97.2)

94.2 (93.2,95.3)

92.3 (91.2, 93.4)

ALT (U/L)

27.7 (26.9, 28.5)

29.4 (28.6, 30.3)

29.3 (28.4, 30.3)

29.2 (28.4, 30.0)

AST (U/L)

25.6 (25.1, 26.1)

25.9 (25.3, 26.4)

25.7 (25.2, 26.3)

26.1 (25.4, 26.9)

Sex

 Female

61.5 (59.2, 63.8)

55.1 (52.7, 57.5)

51.5 (49.5, 53.5)

46.5 (44.3, 48.6)

 Male

38.5 (36.2, 40.8)

44.9 (42.5, 47.3)

48.5 (46.5, 50.5)

53.5 (51.4, 55.7)

Race

 Non-hispanic white people

48.8 (44.9, 52.7)

65.5 (62.3, 68.5)

70.9 (67.7, 73.9)

74.4 (71.2, 77.4)

 Non-hispanic black people

31.9 (28.5, 35.5)

13.7 (11.9, 15.7)

9.7 (8.3, 11.4)

8.1 (6.9, 9.5)

 Mexican American

10.0 (8.4, 11.8)

10.8 (9.1, 12.7)

9.7 (8.0, 11.7)

8.3 (6.7, 10.2)

 Other races

9.4 (7.9, 11.1)

10.1 (8.5, 11.8)

9.7 (8.2, 11.5)

9.2 (7.6, 11.2)

Education levels

 Less than 9th grade

7.0 (6.2, 8.0)

6.8 (5.9, 7.8)

5.5 (4.7, 6.4)

6.4 (5.4, 7.5)

 9–11th grade/high school grade or equivalent

39.7 (37.4, 42.0)

37.1 (34.8, 39.4)

41.6 (39.3, 43.9)

41.6 (39.0, 44.3)

 College graduate or above

53.3 (51.0, 55.5)

56.2 (53.7, 58.6)

52.9 (50.5, 55.3)

52.0 (49.4, 54.6)

Diabetes mellitus

 No

83.2 (81.5, 84.8)

83.4 (81.9, 84.8)

80.8 (79.2, 82.3)

76.3 (74.4, 78.2)

 Yes

16.8 (15.2, 18.5)

16.6 (15.2, 18.1)

19.2 (17.7, 20.8)

23.7 (21.8, 25.6)

CVD

 No

92.6 (91.4, 93.6)

92.5 (91.3, 93.6)

90.0 (88.6, 91.3)

85.9 (84.2, 87.5)

 Yes

7.4 (6.4, 8.6)

7.5 (6.4, 8.7)

10.0 (8.7, 11.4)

14.1 (12.5, 15.8)

Hypertension

 No

55.3 (52.9, 57.6)

54.9 (52.4, 57.5)

51.2 (48.8, 53.6)

46.7 (44.6, 48.8)

 Yes

44.7 (42.4, 47.1)

45.1 (42.5, 47.6)

48.8 (46.4, 51.2)

53.3 (51.2, 55.4)

Hyperlipidemia

 No

19.6 (17.9, 21.4)

20.7 (18.9, 22.7)

18.1 (16.3, 20.0)

17.5 (15.8, 19.3)

 Yes

80.4 (78.6, 82.1)

79.3 (77.3, 81.1)

81.9 (80.0, 83.7)

82.5 (80.7, 84.2)

Smoking

 Never

62.4 (60.4, 64.4)

57.4 (55.2, 59.5)

53.2 (51.0, 55.4)

48.4 (46.0, 50.8)

 Former

20.7 (18.7, 22.7)

24.9 (22.9, 26.9)

26.1 (24.2, 28.1)

28.2 (26.0, 30.5)

 Current

16.9 (15.2, 18.8)

17.8 (16.2, 19.4)

20.7 (18.8, 22.7)

23.4 (21.7, 25.2)

Drinking

 Never

14.0 (11.9, 16.4)

12.9 (11.3, 14.7)

13.4 (11.3, 15.7)

11.5 (10.0, 13.2)

 Former

19.6 (17.4, 22.0)

18.2 (16.2, 20.4)

18.8 (17.0, 20.7)

22.1 (20.1, 24.2)

 Mild/Moderate

30.4 (28.0, 33.0)

32.3 (29.7, 35.0)

32.9 (30.6, 35.2)

31.5 (29.2, 33.9)

 Heavy

36.0 (33.8, 38.3)

36.6 (34.3, 38.9)

35.0 (32.5, 37.6)

34.9 (32.6, 37.3)

Antihypertensives

 No

88.7 (87.2, 90.0)

88.7 (86.9, 90.3)

86.7 (85.1, 88.1)

84.3 (82.7, 85.8)

 Yes

11.3 (10.0, 12.8)

11.3 (9.7, 13.1)

13.3 (11.9, 14.9)

15.7 (14.2, 17.3)

Glucose-lowering drugs

 No

90.7 (89.3, 91.9)

89.4 (88.1, 90.7)

88.2 (86.8, 89.4)

85.4 (83.9, 86.8)

 Yes

9.3 (8.1,10.7)

10.6 (9.3, 11.9)

11.8 (10.6, 13.2)

14.6 (13.2, 16.1)

Lipid-lowering drugs

 No

86.5 (85.2, 87.8)

84.2 (82.2, 85.9)

80.2 (78.2, 82.0)

78.1 (75.9, 80.1)

 Yes

13.5 (12.2, 14.8)

15.8 (14.1, 17.8)

19.8 (18.0, 21.8)

21.9 (19.9, 24.1)