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Table 1 Baseline characteristics according to the BMI categories

From: Association of N-terminal pro-B-type natriuretic peptide levels and mortality risk in acute myocardial infarction across body mass index categories: an observational cohort study

 

Overall n = 4677

 < 18.5 kg/m2 n = 127 (2.7%)

18.5–23.9 kg/m2

n = 1496 (32.0%)

24–27.9 kg/m2

n = 2029 (43.4%)

 ≥ 28 kg/m2 n = 1025 (21.9%)

P value

Clinical characteristics

 Age, years

64.7 (12.5)

75.4 (10.4)

67.7 (12.0)

63.9 (11.9)

60.7 (13.1)

 < 0.001

 Male, n (%)

3405 (72.8)

61 (48.0)

1037 (69.3)

1538 (75.8)

769 (75.0)

 < 0.001

 Hypertension, n (%)

3037 (64.9)

70 (55.1)

885 (59.2)

1335 (65.8)

747 (72.9)

 < 0.001

 Dyslipidemia, n (%)

2062 (44.1)

31 (24.4)

602 (40.2)

919 (45.3)

510 (49.8)

 < 0.001

 Diabetes, n (%)

1566 (33.5)

21 (16.5)

508 (34.0)

679 (33.5)

358 (34.9)

 < 0.001

 Prior MI, n (%)

514 (11.0)

18 (14.2)

168 (11.2)

235 (11.6)

93 (9.1)

0.11

 Current smoker, n (%)

2114 (45.2)

44 (34.6)

630 (42.1)

954 (47.0)

486 (47.4)

 < 0.001

 STEMI, n (%)

2319 (49.6)

64 (50.4)

744 (49.7)

1031 (50.8)

480 (46.8)

0.22

 Killip Class III-IV, n (%)

478 (10.2)

22 (17.3)

170 (11.4)

192 (9.5)

94 (9.2)

0.009

 LM or multivessel disease, n (%)

3441 (73.6)

54 (42.5)

1053 (70.4)

1556 (76.7)

778 (75.9)

 < 0.001

 LVEF, %

58.1 (10.3)

55.5 (13.0)

57.4 (11.0)

58.3 (10.0)

58.7 (9.6)

 < 0.001

 Heart rate, bpm

75.5 (15.1)

77.3 (17.6)

75.8 (16.5)

75.1 (14.3)

75.4 (14.2)

0.28

 SBP, mmHg

128.9 (22.3)

126.3 (23.8)

127.3 (22.6)

128.7 (21.9)

132.0 (22.1)

 < 0.001

 Long-term GRACE risk score

113.6 (27.7)

139.5 (26.1)

120.8 (27.1)

111.2 (26.0)

104.6 (27.6)

 < 0.001

Laboratory values

 FPG, mmol/L

6.8 (2.8)

5.5 (2.0)

6.7 (2.9)

6.9 (2.8)

7.0 (2.8)

 < 0.001

 Hemoglobin, g/L

132.9 (22.5)

116.1 (23.2)

128.4 (22.5)

135.1 (21.9)

137.3 (21.4)

 < 0.001

 eGFR, mL/min/1.73m2

107.2 (36.5)

97.8 (47.1)

104.3 (37.9)

108.6 (35.4)

109.6 (34.8)

 < 0.001

 hs-CRP, mg/L

6.9 (2.3, 19.2)

10.2 (1.4, 19.8)

6.2 (1.8, 19.3)

6.8 (2.3, 19.0)

7.9 (2.8, 19.6)

0.010

 Peak value of hs-TnI, ng/mL

7.6 (1.2, 35.7)

2.7 (0.6, 11.4)

7.3 (1.1, 34.8)

8.3 (1.3, 37.4)

7.6 (1.1, 34.7)

 < 0.001

 Peak value of NT-proBNP, pg/mL

1524 (491, 4787)

8974 (2348, 24123)

2064 (700, 6922)

1348 (455, 3892)

1041 (338, 3007)

 < 0.001

 LDL-C, mmol/L

2.6 (0.8)

2.2 (0.7)

2.5 (0.8)

2.6 (0.8)

2.7 (0.8)

 < 0.001

 HDL-C, mmol/L

1.0 (0.2)

1.2 (0.3)

1.1 (0.3)

1.0 (0.2)

1.0 (0.2)

 < 0.001

 Total cholesterol, mmol/L

4.5 (1.1)

4.1 (1.0)

4.3 (1.1)

4.5 (1.1)

4.6 (1.1)

 < 0.001

 Triglyceride, mmol/L

1.4 (1.0, 2.0)

0.9 (0.7, 1.2)

1.2 (0.9, 1.7)

1.5 (1.1, 2.1)

1.6 (1.2, 2.3)

 < 0.001

Acute treatment

 Aspirin, n (%)

4181 (89.4)

92 (72.4)

1286 (86.0)

1862 (91.8)

941 (91.8)

 < 0.001

 Clopidogrel/Ticagrelor, n (%)

3895 (83.3)

82 (64.6)

1197 (80.0)

1747 (86.1)

869 (84.8)

 < 0.001

 ACEI/ARB, n (%)

2954 (63.2)

50 (39.4)

853 (57.0)

1327 (65.4)

724 (70.6)

 < 0.001

 β-blocker, n (%)

3356 (71.8)

74 (58.3)

1014 (67.8)

1512 (74.5)

756 (73.8)

 < 0.001

 Statins, n (%)

3989 (85.3)

89 (70.1)

1236 (82.6)

1773 (87.4)

891 (86.9)

 < 0.001

 Diuretics, n (%)

586 (12.5)

22 (17.3)

199 (13.3)

244 (12.0)

121 (11.8)

0.22

 PCI, n (%)

3469 (74.2)

52 (40.9)

1037 (69.3)

1595 (78.6)

785 (76.6)

 < 0.001

  1. Values are n (%), mean (SD), or median (interquartile interval)
  2. ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high sensitivity C-reactive protein; hs-TnI, high sensitivity troponin I; LDL-C, low-density lipoprotein cholesterol; LM, left main coronary artery; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NT-proBNP, N-terminal pro-B-type natriuretic peptide; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; STEMI, ST-segment elevated myocardial infarction