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Table 2 Multivariable-adjusted hazard ratios (95% Confidence interval) for the association of ASCVD risk factors and incident atherosclerotic cardiovascular disease among those with type 2 diabetic microvascular complications at baseline

From: Determinants of incident atherosclerotic cardiovascular disease events among individuals with type 2 diabetic microvascular complications in the UK: a prospective cohort study

ASCVD risk factors

ASCVD

Model 1

ASCVD

Model 2

Cigarette smoking-Former/Current

1.23 (1.04–1.45)

1.20 (0.99–1.47)

Hypertension

0.97 (0.73–1.30)

0.95 (0.66–1.37)

Hyperlipidemia

1.24 (0.98–1.57)

1.13 (0.85–1.51)

Family history of ASCVD

1.20 (1.02–1.41)

1.20 (0.98–1.46)

Central Obesity

1.20 (1.00-1.44)

1.09 (0.87–1.37)

Triglycerides, per mmol/L

1.07 (1.01–1.14)

0.99 (0.90–1.09)

HDL-C, per mmol/L

0.59 (0.43–0.80)

0.49 (0.32–0.75)

LDL-C, per mmol/L

1.04 (0.93–1.16)

1.07 (0.91–1.25)

Lipoprotein(a), per 10 mmol/L

1.02 (1.00-1.04)

1.02 (1.00-1.04)

CRP, per mg/L

1.02 (1.01–1.03)

1.01 (0.99–1.02)

Vitamin D, per nmol/L

0.99 (0.99-1.00)

1.00 (0.99-1.00)

Gamma-glutamyltransferase, per 10 U/L

1.01 (1.00-1.02)

1.02 (1.00-1.03)

  1. Model1 is adjusted for age, gender, ethnicity, education, Townsend deprivation index, physical activity, duration of diabetes, diabetes-related medication, and hemoglobin A1c; Model2 is adjusted for age, gender, ethnicity, education, Townsend deprivation index, physical activity, duration of diabetes, diabetes-related medication, hemoglobin A1c, and all listed risk factors. Abbreviations: ASCVD (atherosclerotic cardiovascular disease); HDL-C (high-density lipoprotein cholesterol); LDL-C (low-density lipoprotein cholesterol); CRP (C-reactive protein). BOLDED items are significant statistically significant (P < 0.05)
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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