Table 1 The clinical characteristics of study participants in the different Leiden score groups
Overall (n = 427) | Leiden score < 5 (n = 138) | Leiden score ≥ 5 (n = 289) | P Value | |
|---|---|---|---|---|
Age (year) | 78.54 ± 10.11 | 78.88 ± 10.39 | 0.39 | |
Smoking (%) | 158(37.00%) | 51(36.95%) | 107(37.02%) | 0.26 |
Hypertension (%) | 299(70.02%) | 97(70.28%) | 203(70.24%) | 0.62 |
Dyslipidemia (%) | 264(61.83) | 85(61.59%) | 179(61.93%) | 0.58 |
Diabetes (%) | 137(32.08%) | 44(31.88%) | 93(32.17%) | 0.15 |
BMI | 25.45 ± 3.38 | 25.58 ± 3.59 | 25.32 ± 3.28 | 0.42 |
Fasting blood glucose, mg/dl | 110.72 ± 39.22 | 107.64 ± 37.44 | 113.76 ± 42.48 | 0.11 |
HbA1c | 6.36 ± 0.88 | 6.05 ± 0.76 | 7.04 + 0.90 | < 0.01 |
TC, mg/dl | 160.869 ± 38.47 | 173.18 ± 38.27 | 168.55 ± 39.04 | 0.20 |
TG, mg/dl | 128.46 (82.82, 171.88) | 136.44 (83.28, 177.2) | 120.49 (80.11,166.56) | 0.08 |
LDL-C, mg/dl | 93.36 ± 28.27 | 92.42 ± 27.45 | 93.58 ± 29.00 | 0.63 |
HDL-C, mg/dl | 49.92 ± 14.67 | 51.04 ± 15.85 | 49.11 ± 11.98 | 0.08 |
eGFR-EPI, mL/min/1.73 m2 | 90.23(79.30, 98.42) | 90.09(78.11, 99.01) | 90.36(79.41, 9855) | 0.78 |
Uric acid, umol/L | 335.24 ± 76.37 | 331.81 ± 81.07 | 337.49 ± 73.29 | 0.44 |
TyG index | 8.73 ± 0.62 | 8.77 ± 0.65 | 8.71 ± 0.57 | 0.55 |
Statins use (%) | 262(61.35%) | 83(60.14) | 179(61.93) | 0.22 |
Ezetimibe use (%) | 18(42.15%) | 6(4.34) | 12(4.15) | 0.71 |