Salari Paper Results (N) | New Resultsa (N) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Study | Year | Groups (Salari Paper) | Groups (New Resultsa) | Total Patients | Men (N) | Women (N) | Total Patients | Men (N) | Women (N) |
Apovian [9] | 2013 | Placebo | Placebo | 1496 | 76 | 419 | 1496 | 76 | 419 |
Naltrexone + bupropion | 32 mg/day naltrexone SR + 360 mg/day bupropion SR (NB32) | 155 | 846 | 155 | 846 | ||||
Aronne [10] | 2010 | Placebo | Placebo | 244 | 13 | 87 | 244 | 8 | 55 |
Pramlintide | Pramlintide (120 µg sc) | 12 | 88 | 7 | 54 | ||||
Pramlintide (120 µg sc t.i.d.) + sibutramine (10 mg oral q.a.m.) | 6 | 53 | |||||||
Pramlintide (120 µg sc t.i.d.) + phentermine (37.5 mg oral q.a.m.) | 8 | 53 | |||||||
Davies [17] | 2015 | Placebo | Placebo | 864 | 97 | 115 | 846 | 97 | 115 |
Liraglutide 0.3 mg | Liraglutide 3.0 mg | 220 | 203 | 220 | 203 | ||||
Liraglutide 1.8 mg | Liraglutide 1.8 mg | 108 | 103 | 108 | 103 | ||||
Fidler [11] | 2011 | Placebo | Placebo | 4004 | 353 | 1248 | 4004 | 353 | 1248 |
Lorcaserin 10 mg BID | Lorcaserin 10 mg BID | 313 | 1289 | 313 | 1289 | ||||
Lorcaserin 10 mg QD | Lorcaserin 10 mg QD | 145 | 656 | 145 | 656 | ||||
Gadde [12] | 2011 | Placebo | Placebo | 2487 | 299 | 695 | 2487 | 299 | 695 |
Phentermine 7.5 mg + topiramate 46.0 mg | Phentermine 7.5 mg + topiramate 46.0 mg | 149 | 349 | 149 | 349 | ||||
Phentermine 15.0 mg + topiramate 92.0 mg | Phentermine 15.0 mg + topiramate 92.0 mg | 302 | 693 | 302 | 693 | ||||
Greenway [8] | 2010 | Placebo | Placebo | 1742 | 85 | 496 | 1742 | 85 | 496 |
Naltrexone + bupropion 16.0 mg | Naltrexone16.0 mg + bupropion | 88 | 490 | 88 | 490 | ||||
Naltrexone + bupropion 32.0 mg | Naltrexone32.0 mg + bupropion | 87 | 496 | 87 | 496 | ||||
Le Roux [13] | 2017 | Placebo | Placebo | 2254 | 176 | 573 | 2254 | 176 | 573 |
Liraglutide | Liraglutide 3.0 mg | 364 | 1141 | 364 | 1141 | ||||
Lu [14] | 2018 | Placebo | Placebo | 171 | 28 | 57 | 170 | 28 | 57 |
Lorcaserin | Lorcaserin 10.0 mg | 39 | 46 | 39 | 46 | ||||
O’Neil [15] | 2012 | Placebo | Placebo | 508 | 73 | 84 | 603 | 115 | 137 |
Orlistat 120.0 mg BID | Lorcaserin 10 mg BID | 86 | 83 | 119 | 137 | ||||
Orlistat 120.0 mg QD | Lorcaserin 10 mg QD | 34 | 41 | 42 | 53 | ||||
Pi-Sunyer [16] | 2015 | Placebo | Placebo | 3731 | 273 | 971 | 3731 | 273 | 971 |
Liraglutide | Liraglutide 3.0 mg QD | 530 | 1957 | 530 | 1957 | ||||
Smith [17] | 2010 | Placebo | Placebo | 3182 | 253 | 1331 | 3182 | 253 | 1331 |
Lorcaserin | Lorcaserin 10.0 mg | 272 | 1321 | 272 | 1321 |