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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats

Fig. 3

Effect of DAPA or DAPA combined with exercise on the expression of atrophy-associated proteins in the extensor digitorum longus muscle of rats. The quantification of FoXO3A, FoXO1, NF-κB, and MuRF1 proteins is depicted in panels (A), (D), (E), and (F), respectively. The phosphorylation levels of the FoXO3A protein are shown in panel (B), while the relative expression of p-FoXO3A protein is shown in panel (C). GAPDH was employed as an internal control. All data are shown as the mean ± SEM (n = 6 per group), and statistical analysis involved a one-way ANOVA test with Tukey’s post hoc evaluation (*P < 0.05)

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