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Table 2 Clinical, treatment and laboratory differences in patients with and without coronary artery disease determined by electrocardiogram

From: Pragmatic clinic-based investigation of echocardiogram parameters in asymptomatic patients with type 2 diabetes in routine clinical practice and its association with suggestive coronary artery disease: a pilot study

Demographic data

N = 11

N = 123

p

Males, n (%)

8 (72.7)

46 (37.4)

0.022

Age (years)

57.55 ± 8.99

55.54 ± 9.65

0.448

Age at diagnosis (years)

42.55 ± 8.89

43.15 ± 10.71

0.780

Known duration of diabetes (years)

12.64 ± 8.43

12.65 ± 8.38

0.318

Years of school attendance

9.73 ± 3.74

9.54 ± 4.58

0.594

Self-reported color-race (white/non-white), n (%)

54.5/45.5

39/71

0.315

Positive family history (FH)

   

 FH of type 2 diabetes, n (%)

10 (90.9)

86 (69.9)

0.139

 FH of obesity, n (%)

5 (45.5)

56 (45.5)

0.996

 FH of hypertension, n (%)

9 (81.8)

91 (74.0)

0.567

 FH of premature CAD, n (%)

3 (27.3)

48 (39.0)

0.442

Anthropometric data

   

 BMI (kg/m2)

30.77 ± 6.24

30.54 ± 5.11

0.932

 SBP (mmHg)

137.18 ± 17.56

132.25 ± 16.00

0.260

 DBP (mmHg)

82.27 ± 11.02

78.73 ± 9.61

0.290

 Waist (cm)

99.18 ± 15.60

99.60 ± 1.05

0.955

 WHR (cm)

0.98 ± 0.13

0.97 ± 0.09

0.894

Classic cardiovascular risk factors

   

 Hypertension, n (%)

9 (81.8)

93(75.6)

0.644

 Dyslipidemia, n (%)

11 (100)

106 (86.2)

0.187

 Current smokers, n (%)

1 (9.1)

9 (7.3)

0.830

 Sedentary lifestyle, n (%)

6 (54.5)

90 (73.2)

0.189

 Current alcohol consumption, n (%)

4 (36.4)

52 (42.3)

0.703

Treatment data

   

 Basal insulin, n (%)

8 (72.7)

66 (53.7)

0.234

 Metformin, n (%)

11 (100)

115 (93.5)

0.414

 Statins, n (%)

11 (100)

95 (77.2)

0.075

 Antihypertensive drugs, n (%)

9 (81.8)

93 (75.6)

0.644

 Aspirin, n (%)

5 (45.5)

42 (34.1)

0.502

Diabetes-related chronic complications

   

 Retinopathy, yes, n (%)

7 (63.6)

36 (29.3)

0.022

 Diabetic renal Disease (GFR < 60 ml/min), n (%)

3 (27.27)

17 (13.8)

0.247

 Neuropathy (self-reported of symptoms), n (%)

5 (81.8)

55 (45.8)

0.385

Laboratory data

   

 Fasting glucose (mg/dl)

186 (129)

142 (101)

0.134

 HbA1c (%)

8.78 ± 1.83

7.96 ± 1.67

0.146

 Total cholesterol (mg/dl)

225.73 ± 72.23

187.44 ± 54.81

0.109

 Triglycerides (mg/dl)

228 (469)

160 (116)

0.026

 HDLc (mg/dl)

58.79 ± 1.41

59.31 ± 1.87

0.920

 Non-HDLc (mg/dl)

168.9 ± 73.46

133.96 ± 54.49

0.182

 LDLc (mg/dl)

105.00 ± 49.75

95.55 ± 4.22

0.383

 Uric acid (mg/dl)

7.98 ± 3.30

6.15 ± 2.11

0.061

 Albumin (g/dl)

5.28 ± 1.17

4.75 ± 0.99

0.112

 Albuminuria (mg/g)

26.81 ± 2.19

37.32 ± 6.48

0.071

  1. Data are presented as mean ± SD or median and interquartile range(IQR)
  2. FH family history, CAD coronary artery disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, WHR waist to hip ratio, GFR glomerular filtration rate, HDLc high density cholesterol, LDLc low density cholesterol, CRP C protein, CIMT carotid intima-media thickness, IMT intima-media thickness, FRS Framingham risk score, VA vascular age, EF ejection fraction