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Table 5 Multinomial logistic regression to identify variables that were associated with a greater probability of receiving RAAS blocker or SGLT2 inhibitor versus receiving neither in this population, and receiving the combination of both (complete nephroprotective treatment)

From: Treatment patterns of antidiabetic and kidney protective therapies among patients with type 2 diabetes mellitus and chronic kidney disease in Colombia. The KDICO descriptive study

 

Variable

B

Siga

OR b

95% CI c

Lower

Upper

SLGT2d Inhibitor or RAASe blocker

Intersection

-0.57

    

Gender: male

-0.11

0.02

0.90

0.82

0.98

Age (years)

0.01

0.00

1.01

1.01

1.02

Hypertension

0.85

0.00

2.34

2.13

2.58

Obesity

0.54

0.02

1.72

1.11

2.66

Use of aspirin

0.66

0.00

1.93

1.76

2.12

Use of β-blockers

0.16

0.00

1.18

1.06

1.31

Use of Proton Pump Inhibitors

0.10

0.04

1.11

1.01

1.22

Use of metformin

0.33

0.00

1.39

1.27

1.53

Use of insulin

-0.17

0.00

0.85

0.77

0.93

Be treated in Bogota-Cundinamarca region

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Be treated in the Caribe region

0.05

0.51

1.06

0.90

1.24

Be treated in the Central region

-0.16

0.04

0.85

0.73

0.99

Be treated in the Oriental region

-0.04

0.80

0.96

0.74

1.27

Be treated in the Pacific region

0.25

0.00

1.28

1.12

1.47

Complete treatment (ACEif or ARBg + SGLT2i)

Intersection

-1.29

    

Gender: male

0.03

0.67

1.03

0.91

1.16

Age (years)

-0.02

0.00

0.98

0.98

0.99

Dementia

-0.54

0.01

0.58

0.38

0.88

Dyslipidemia

0.65

0.00

1.91

1.52

2.40

Hypertension

0.97

0.00

2.63

2.29

3.03

Obesity

1.15

0.00

3.14

1.96

5.05

Use of aspirin

0.93

0.00

2.53

2.23

2.88

Use of β-blockers

0.25

0.00

1.28

1.12

1.47

Use of Proton Pump Inhibitors

0.15

0.02

1.17

1.03

1.32

Use of metformin

0.61

0.00

1.83

1.61

2.08

Use of insulin

0.97

0.00

2.63

2.31

3.00

Be treated in Bogota-Cundinamarca region

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Be treated in the Caribe region

-0.28

0.02

0.76

0.60

0.96

Be treated in the Central region

0.13

0.22

1.14

0.93

1.39

Be treated in the Oriental region

0.13

0.50

1.13

0.79

1.63

Be treated in the Pacific region

0.54

0.00

1.72

1.44

2.07

  1. a significance level. b OR: Odds ratio. c 95% confidence interval. d SGLT2: sodium-glucose cotransporter type 2; e RAAS blocker: renin angiotensin aldosterone system blocker. f ACEis: angiotensin converting enzyme inhibitors. g ARBs: angiotensin receptor blockers