Fig. 5
From: Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B
Effects of ADSCs-Exo and high glucose treatment on Keap1 expression and Keap1-NrF2 binding in podocytes
(A) WB was used to detect the effect of ADSCs-Exo and high glucose treatment on Keap1 protein expression in MPC5 cells, and GAPDH was used as an internal control. (B) CO-IP was used to detect the effect of ADSCs-Exo and high glucose on Keap1-Nrf2 binding in MPC5 cells, with input as the internal control. Data were presented as Mean ± SD, and one-way analysis of variance was used to detect statistical differences between groups. ns p > 0.05 VS. NG; ** p < 0.01 VS. NG; ## p < 0.01 VS. HG.