Fig. 8From: Therapeutic effects on the development of heart failure with preserved ejection fraction by the sodium-glucose cotransporter 2 inhibitor dapagliflozin in type 2 diabetesMetabolomics revealed the effects of dapagliflozin on serum metabolite profiles. a Heatmap for differentially expressed metabolites. Each row represents a metabolite marker, and each column represents a loading sample. b Volcano plots of the metabolomics data for the pairwise comparison. Up-regulated and down-regulated proteins are marked with red and blue colors, respectively. c Top 20 significant functional pathways enriched by differentially expressed metabolitesBack to article page