Klotho and SIRT1 changes from pre-diabetes to diabetes and pre-hypertension to hypertension

Table 2 Linear regression of serum Klotho or SIRT1 level, as dependent variables, with age, BMI, FBS, MAP in studied groups

Dependent variable	Predictor	USC Beta	SE	SC Beta	P value
Klotho	Age	− 0.072	0.031	− 0.123	0.019
	BMI	− 0.331	0.109	− 0.159	0.003
	FBS	− 0.037	0.008	− 0.246	0.000
	MAP	− 0.067	0.022	− 0.155	0.002
	Log of SIRT1	20.704	1.857	0.554	0.000
SIRT1	Age	0.000	0.001	0.025	0.663
	BMI	0.003	0.003	0.050	0.387
	FBS	0.001	0.000	0.143	0.012
	MAP	0.000	0.001	0.023	0.674
	SqR of Klotho	0.017	0.002	0.648	0.000

USC Beta unstandardized regression coefficient; SC Beta standardized coefficient; SE standard errors of the regression coefficients; Klotho SqR Klotho square root, SIRT 1 Log SIRT 1 logarithm, FBS fasting blood sugar; BMI body mass index; MAP mean arterial pressure

ISSN: 1758-5996